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Ljiljana Hajduković

Organisation Group: Department for immunochemistry and glycobiology

Academic Degree: Graduated Pharmacist, PhD in Biochemistry

Current Position: Senior Research Associate

Other responsibilities: Deputy director for laboratory analyses

Education: Graduated from Faculty of Pharmacy, University of Belgrade, 1982.

M.Sc. in Biochemistry: “Characterization and separation of glycoproteins using affinity chromatography with immobilized lectins”,
Faculty of Chemistry, University of Belgrade, 1990.

PhD in Biochemistry: “Study of human serum glycoproteins: chorionic gonadotropin, transferrin and immunoglobulin G glycosylation, using lectin affinity methods”,  Faculty of Chemistry, University of Belgrade, 1999.

Specialization: Protein Laboratory, University of Copenhagen, Denmark (research leader Prof. Dr Thorkild Bog-Hansen). Research field: microheterogeneity of alkaline phosphatase, lectin affinity electrophoresis.

Membership in International and National Societies:

Member of the Society of Medical Biochemists of Serbia

Research Field:

Lectinology and glycobiology. The application of lectins with known carbohydrate specificities in examination of structure of serum glycoproteins, such as immunoglobulin G, IGFBP and PSA. Examination of variations of carbohydrate moieties of glycoproteins in connection with certain physiological and pathological conditions. Determination and characterization of antibodies connected with the disease Myasthenia gravis (antibodies to acetylholine receptor and antibodies to muscle-specific tyrosine kinase).

Professional Activities:

Participates in the national project: Structural heterogeneity and effects of complex carbohydrates (glycans) as key components of molecular recognition in biological systems (project number 173010, Ministry of Education, Science and Technological Development of Republic of Serbia, 2011-2017).

Bibliography:

Lavrnić, D., Nikolić, A., De Baets, M., Verschuuren, J., Verduyn, W., Losen, M., Stojanović, V., Stević, Z., Hajduković-Dragojlović, Lj., Apostolski, S.: Familial occurrence of autoimmune Myasthenia gravis with different antibody specificity; Neurology 70, 2011-2013 (2008).

Hajduković, Lj.: Prostate-specific antigen (PSA): Role in diagnosis and monitoring of prostate diseases: Current trends in tumor marker diagnosis: experience of  FP6  HISERBS project, 44-78 (2009).

Nikoloć, A., Đukić, P., Basta, I., Hajduković, Lj., Stojanović, VR., Stević, Z., Nikolić, D., Božić, V., Lavrnić, S., Lavrnić, D.: The predictive value of the presence of different antibodies and thymus pathology to the clinical outcome in patients with generalized myasthenia gravis; Clin Neurol Neurosurg (2012).

Grga, Dj., Dželetović, B., Damjanov, M., Hajduković, Lj.: Prostaglandin E2 in apical tissue fluid and postoperative pain in intact and teeth with large restorations in two endodontic treatment visits; Srp Arh Celok Lek 141, 15-19 (2013).

Goč, S., Kosanović, M., Golubović, S., Hajduković, Lj., Janković, M.: Determination of prostate-specific antigen in serum and a reference material by on-chip immunoaffinity chromatography; Analytical Letters 47 (18), 2919-2928 (2014).

Golubović, S., Hajduković, Lj., Goč, S., Janković, M.: Metrological traceability – experience of accredited laboratory of the Institute for the application of nuclear energy (INEP); International Convention on Quality (2017).