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  • Ninoslav Mitić

Ninoslav Mitić

Organization Group: Department of Immunochemistry and Glycobiology

Academic Degree: Graduated biologist and microbiologist, Phd in biological sciences

Current position: Research Associate

Education: Graduated at the Faculty of Biology, study group for Microbiology, University of Belgrade. “Antibacterial effect of 2- alkylidene-4-oxothiazolidines and buckwheat (Fagopyrum esculentum Moench) seed flakes extract“, 2007.

PhD at Faculty of Biology, University of Belgrade: “Bioinformatic and glycobiochemical analysis of human CA125 antigen modular
organization
”, 2012.

Research field:

Member of a team of researchers oriented on fundamental and applied science, that are focused on glycosylation of CA125 antigen, its expression, microheterogeneity, interactions and biosignaling properties of CA125-associated glycans in health and disease. Previous research was focused on bioinformatic and glycobiochemical analysis of the human CA125 antigen modular organization. Current and future research represents further efforts in characterization of mucin molecules found on or associated with microvesicles from seminal plasma (prostasomes) and amniotic fluid (exosomes), as well as their potential role as ligands in protein-protein and protein-carbohydrate interactions with endogenous receptors of immune system.

Memberships:

Member of the Serbian Biochemical Society
Member of the Serbian Biological Society

Bibliography (2010-2017):

Mitić N, Kosanović M, Milutinović B, Goč S, Mladenović D, Grubiša I, Janković M (2018) Nano-sized CA125 antigen glycocamouflage: Mucin – Extracellular vesicles alliance to watch? Arch Biochem Biophys 653:113-120

Kosanovic M, Milutinovic B, Goc S, Mitic N, Jankovic M. (2017) Ion-exchange chromatography purification of extracellular vesicles. BioTechniques 63:65-71.

Mitić N, Milutinović B, Janković M. (2017) Analysis of CA125 antigen in normal human seminal plasma highlights the molecular heterogeneity of underlying glycosylated species. Turk J Biol 41:543-551.

Milutinovic B, Mitić N, Roncevic J, Goc S, Jankovic M. (2016) Glycome complexity of human seminal plasma high molecular mass components: Evaluation of the contribution of acid-soluble glycoproteins/mucins and extracellular vesicles. Arch Biochem Biophys 609:20-30.

Mitić N, Milutinović B, Janković M. (2014) CA-125 of fetal origin can act as a ligand for dendritic cell-specific ICAM-3-grabbing non-integrin. Cell Mol Biol Lett 19(2):249-61.

Jankovic M, Mitic N. (2012) MUC16/CA125 in the Context of Modular Proteins with an Annotated Role in Adhesion-Related Processes: In Silico Analysis. Int J Mol Sci 13(8):10387-10400.

Mitić N, Milutinović B, Janković M. (2012) Assessment of sialic acid diversity in cancer- and non-cancer related CA125 antigen using sialic acid-binding Ig-like lectins (Siglecs). Dis Markers 32(3):187-94.

Mitić N, Janković M. (2010) Activity profile of the CA125 antigen towards human red blood cells. Arch Biol Sci 62 (2):271-280.

Milutinović B, Mitić N, Janković M. (2010) Identification of pregnancy-associated CA125-reactive protein as a carbohydrate-binding immunoglobulin G. Arch Biochem Biophys; 499: 69–76.