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  • Olgica Nedić

Olgica Nedić

Organisation Group:  Department for Metabolism

Academic Degree:  Graduated Chemist, PhD in Biochemistry

Current Position:  Principal Research Fellow

Leading positions: Director of the Institute and Head of Department for Metabolism
Research theme leader: “Proteins and nucleic acids in metabolic disorders and mechanisms of their regulation” 

Education: Graduated at Faculty for Natural Sciences (Chemistry), University of Belgrade in 1985. M. Sc Thesis in Biochemistry finished in 1988. and PhD Thesis in 1994. at Faculty of Chemistry, University of Belgrade.

Research Field:

Participates in the research group involved in basic and applied investigations on insulin, insulin-like growth factors and other proteins involved in metabolic processes. The activities focus on the effects of various physiological and disease states on metabolism in men and animals (ageing, intensive training, pregnancy, diabetes, cancer, diseases accompanied by oxidative stress) and the analysis of the potential effect of small molecules from the microenvironment. Besides the investigation on proteins, the research is carried out on noncoding nucleic acids and their association with metabolic disorders.

Membership in International and National Societies:

Member of the International Society for Insulin-Like Growth Factors (since 2003)
Member of the Serbian Chemical Society (since 1985)
Member of the Serbian Biochemical Society (since 2011)

Other responsibilities:

Member of the National Council for Scientific Certification of Research Institutions (under auspicious of Ministry of Science, 2006-2010)
Member of the Professional Board for the Scientific Field of Biotechnology (under auspicious of the University of Belgrade, 2007-2010)
Sub-Editor of the Journal of the Serbian Chemical Society for Biochemistry and Biotechnology (since 2006)
Member of the Council for Quality Improvement of the University of Belgrade (2008-2011)
Member of the National Scientific Council for Chemistry (under auspicious of the Ministry of Science, 2010-2016)
Member of the University Council (under auspicious of the University of Belgrade, 2016-2018)
Member of the National Scientific Council for Biology (under auspicious of the Ministry of Science, since 2017)
Member of INEP Management Board (2011-2017)
Member of the Serbian Chemical Society Management Board (since 2000)

Bibliography (2013-2019):

Gligorijević N., Minić S., Robajac D., Nikolić M., Ćirković Veličković T., Nedić, O., Characterisation and the effects of bilirubin binding to human fibrinogen. Int J Biol Macromol 2019, 128:74-79.

Penezić A., Križakova M., Miljuš G., Katrlik J., Nedić O., Diagnostic potential of transferrin glycoforms – a lectin-based protein microarray approach. Proteom Clin Appl 2019, 13:Art. No. 1800185.

Šunderić M., Robajac D., Gligorijević N., Miljuš G., Nedić O., Smilkov K., Gjorgieva Ackova D., Rudić-Grujić V., Penezić A., Is there something fishy about fish oil? Curr Pharmaceut Design 2019, 25:1747-1759.

Šunderić M., Križakova M., Malenković V., Ćujić D., Katrlik J., Nedić O., Changes due to ageing in the glycan structure of alpha-2-macroglobulin and its reactivity with ligands. Prot J 2019, 38:23-29.

Gligorijević N., Šunderić M., Vilotić A., Baralić M., Nedić O., Quantitation of the active alpha-2-macroglobulin by trypsin protease zymography. J Serb Chem Soc 2019, 84:943-950.

Gligorijević N., Robajac D., Nedić O., An enhanced platelet sensitivity to IGF-I in patients with diabetes mellitus. Biochemistry 2019, 84:1213-1219.

Robajac D., Masnikosa R., Nemčovič M., Križáková M., Belická Kluková L., Baráth P., Katrlik J., Nedic O., Glycoanalysis of the placental membrane glycoproteins throughout placental development. Mech Age Develop 2019, 83:Art. no. 111151.

Ausloos M., Nedic O., Dekanski A., Correlations between submission and acceptance of papers in peer review journals. Scientometrics 2019, 119:279-302.

Ausloos M., Nedic O., Dekanski A., Seasonal entropy, diversity and inequality measures of submitted and accepted papers distributions in peer review journals. Entropy 2019, 21:Art. No. 564.

Lagundžin D., Hu W., Law H. C. H., Krieger K., L., Qiao F., Clement E. J., Drincic A. T., Nedić O., Naldrett M. J., Alvarez S., Woods T. N., Delineating the role of FANCA in glucose-stimulated insulin secretion in B cells through its protein interactome. PLoS ONE 2019, 12:Art. no. 0220568.

Drvenica I., Bravo G., Vejmelka L., Dekanski A., Nedić O., Peer review of reviewers: the author’s perspective. Publications 2019, 7:Art. No. 1, doi:10.3390/publications7010001.

Drvenica I. T., Dekanski A. B., Budjevac N., Umeljić I., Nedić O., Is there a need for systematic education on peer-reviewing in Serbia? Hem ind 2019, 73:275-279.

Gligorijević N., Zámorová Križáková M., Penezić A., Katrlík J., Nedić O., Structural and functional changes of fibrinogen due to aging. Int J Biol Macromol 2018, 108:1028-1034.

Gligorijević N., Minić S., Križáková M., Katrlík J., Nedić O., Structural changes of fibrinogen as a consequence of cirrhosis. Thromb Res 2018, 166:43-49.

Nedić O, Drvenica I., Ausloos M., Dekanski A., Efficiency in managing peer-review of scientific manuscripts – editors’ perspective. J Serb Chem Soc 2018, 83:1391-1405.

Nedić O., Šunderić M., Miljuš G., Penezić A., Gligorijević N., Robajac D., Application of the lectin-affinity techniques: advances in the analysis and understanding of the insulin-like growth factor (IGF) system. In: Advances in Medicine and Biology Vol. 131. Nova Science Publishers, Hauppauge, NY. Editor: Leon V. Berhardt. 2018. p. 1-100. ISBN: 978-1-53613-840-5.

Robajac D., Zamorova M., Katrlik J., Miković Ž., Nedić O. Screening for the best detergent for the isolation of placental membrane proteins. Int J Biol Macromol, 2017, 102:431-437.

Penezić A., Miljuš G., Milutinović B., Nedić O., A microscale protocol for the isolation of transferrin directly from serum. Clin Chim Acta, 2017, 471:12-16.

Nedić O., Šunderić M., Miljuš G., Valdevit Z., Jakovljević V., Glibetić M., Vučić V. Preparatory training attenuates drastic response of the insulin-like growth factor binding protein 1 at the point of maximal oxygen consumption in handball players. J Sport Health Sci, 2017, 6:372-377.

Mrowinski M., Fronczak P., Fronczak A., Ausloos M., Nedić O., Artifical intelligence in peer review: how can evolutionary computation support journal editors. PLoS ONE, 2017, 12:Art. no. e0184711.

Robajac D., Gligorijević N., Dželetović Ž., Andrejić G., Nedić O., Separation of peroxidases from Miscanthus x giganteus, their partial characterisation and application for degradation of dyes. Plant Physiol Biochem, 2017, 120:179-185.

Gligorijević N., Penezić A., Nedić O., Influence of glyco-oxidation on complexes between fibrin(ogen) and insulin-like growth factor binding protein-1 in patients with diabetes mellitus type 2. Free Rad Res, 2017, 51:64-72.

Zamorova M., Holazova A., Miljuš G., Robajac D., Šunderić M., Malenković V., Djukanović B., Gemeiner P., Katrlik J., Nedić O., Analysis of changes in glycan composition of serum, cytosol and membrane glycoprotein biomarkers of colorectal cancer by lectin-based protein microarray. Anal Methods, 2017, 9:2660-2666.

Nedić O., Šunderić M., Gligorijević N., Malenković V., Miljuš G. Analysis of four circulating complexes of the insulin-like growth factor binding proteins in human blood during ageing. Biochemistry (Moscow), 2017, 10:1200-1206.

Ausloos M., Nedić O., Dekanski A. A day of the week effect in paper submission/acceptance/rejection to/in/by peer review journals. II. An ARCH econometric-like modelling. Physica A: Statis Mech Appl, 2017, 468:462-474.

Robajac D., Vanhooren V., Masnikosa R., Miković Ž., Mandić V., Libert C., Nedić O. Preeclampsia transforms membrane n-glycome in human placenta. Exp Mol Pathol, 2016, 100:26-30.

Robajac D., Nedić O., Miković Ž., Masnikosa R. Gestation-associated changes in the glycosylation of placental insulin and insluin-like growth factor receptors. Placenta, 2016, 39:70-76.

Šunderić M., Šediva A., Robajac D., Miljuš G., Gemeiner P., Nedić O., Katrlik J. Lectin-based protein microarray analysis of differences in serum alpha-2-macroglobulin glycosylation between patients with colorectal cancer and noncancer persons. Biotechnol Appl Biochem, 2016, 63:457-464.

Nedić O., Miljuš G., Malenković V. Regulation of insulin and insulin-like activity in malnourished patients with carcinoma ventriculi subjected to total gastrectomy and personalized nutritional support. J Med Biochem, 2016, 35:17-25.

Gligorijević N., Nedić O. Interaction between fibrinogen and insulin-like growth factor-binding protein-1 in human plasma under physiologic conditions. Biochemistry (Moscow), 2016, 81:135-140.

Ausloos M., Nedić O., Fronczak A., Fronczak P., Quantifying the quality of peer reviewers through zipf’s law. Scientometrics, 2016, 106:347-368.

Nedić O., Dekanski A. Priority criteria in peer review of scientific articles. Scientometrics, 2016, 107:15-26.

Mrowinski M., Fronczak A., Fronczak P., Nedić O., Ausloos M. Review time in peer review: quantitative analysis and modelling of editorial workfows. Scientometrics, 2016, 107:271-286.

Ausloos M., Nedić O., Dekanski A. A day of the week effect in paper submission/acceptance/rejection to/in/by peer review journals. Physica A: Statist Mech Appl, 2016, 456:197-203.

Dekanski A., Drvenica I., Nedić O. Peer-review process in journals dealing with chemistry and related subjects published in Serbia. Chem Ind Chem Eng Quart, 2016, doi. 10.2298/CICEQ160328033D.

Gligorijević N., Penezić A., Nedić O. Influence of glyco-oxidation on complexes between fibrin(ogen) and insulin-like growth factor binding protein-1 in patients with diabetes mellitus type 2. Free Rad Res, 2016, 5:1-28.

Šunderić M., Malenković V., Nedić O. Complexes between insulin-like growth factor binding proteins and alpha-2-macroglobulin in patients with tumor. Exp Mol Pathol, 2015, 98:173-177.

Miljuš G., Malenković V., Djukanović B., Kolundžić N., Nedić O. IGFBP-3/transferrin/transferrin receptor 1 complexes as principal mediators of IGFBP-3 delivery to colon cells in non-cancer and cancer tissue. Exp Mol Pathol, 2015, 98:431-438.

Robajac D., Masnikosa R., Miković Ž., Mandić V., Nedić O. Oxidation of placental insulin and insulin-llike growth factor receptors in mothers with diabetes mellitus or preeclampsia complicated with intrauterine growth restriction. Free Rad Res, 2015, 49:984-989.

Nedić O., Dekanski A. A survey on the publishing policies of the Journal of the Serbian Chemical Society-On the occasion of the 80th volume. J Serb Chem Soc, 2015, 80:959-969.

Nedić O., Rogowska-Wrzesinska A., Rattan S.I.S. Standardization and quality control in quantifying non-enzymatic oxidative protein modifications in relation to ageing and disease: Why is it important and why is it hard. Redox Biol, 2015, 4:91-100.

Robajac D., Masnikosa R., Vanhooren V., Libert C., Miković Ž., Nedić O. The N-glycan profile of placental membrane glycoproteins alters during gestation and ageing. Mech Ageing Develop, 2014, 138:1-9.

Šunderić M., Djukanović B., Malenković V., Nedić O. Molecular forms of insulin-like growth factor-binding protein-2 in patients with colorectal cancer. Exp Mol Pathol, 2014, 96:48-53.

Šunderić M., Mihailović N., Nedić O. Protein molecular forms of the insulin-like growth factor binding protein 2 change with ageing. Exp Gerontol, 2014, 58:154-158.

Rogowska-Wrzesinska A., Wojdyla K., Nedić O., Baron C.P., Griffiths H. Analysis of protein carbonylation-pitfalls and promise in commonly used methods. Free Rad Res, 2014, 48:1145-1162.

Miljuš G., Malenković V., Nedić O. The importance of metal ion for the formation and isolation of insulin-like growth factor-binding protein 3/transferrin (IGFBP-3/TF) complexes, and the analysis of their physiological involvement. Metallomics, 2013, 5:251-258.

Nedić O., Robajac D., Šunderić M., Miljuš G., Djukanović B., Malenković V. Detection and identification of the oxidized insulin-like growth factor binding proteins and receptors in patients with colorectal carcinoma. Free Rad Biol Med, 2013, 65:1195-1200.

Lagundžin D., Vučić V., Glibetić M., Nedić O. Alteration of IGFBP-1 in soccer players due to intensive training. Int J Sport Nutr Exerc Metab, 2013, 23:449-457.

Nedić O., Rattan S.I.S., Grune T., Trougakos I.P. Molecular effects of advanced glycation end products (AGEs) on cell signalling pathways, ageing and pathophysiology. Free Rad Res, 2013, 47 (Suppl.1):28-38.

Nedić O., Malenković V., Djukanović B., Baričević I. Ligand-binding activity and immunoreactivity of the insulin-like growth factor binding proteins in patients with colorectal carcinoma and post-operative sepsis. J Med Biochem, 2013, 32:250-255.

Šunderić M., Miljuš G., Nedić O. Interaction of insulin-like growth factor-binding protein 2 with alpha 2-macroglobulin in the circulation. Prot J, 2013, 32:138-142.


ORCID ID:  0000-0003-2042-0056