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Olgica Nedić

Organizaciona jedinica: Odeljenje za metabolizam

Profil/Akademsko zvanje: Diplomirani hemičar, doktor biohemijskih nauka

Naučno zvanje: Naučni savetnik

Rukovodeće funkcije: Direktor Instituta i Načelnik Odeljenja za metabolizam
Rukovodilac nacionalnog projekta iz biologije: „Strukturne karakteristike vezujućih proteina i receptora za insulinu slične faktore rasta (IGF), njihove interakcije sa drugim fiziološkim molekulima i promene kod poremećaja metabolizma“ (projekat br. 173042 kod MPNTR Republike Srbije, 2011-2019).

Osnovne studije: Završila Prirodno-matematički fakultet Univerziteta u Beogradu 1985. godine, magistrirala 1988. i doktorirala 1994. godine na Hemijskom fakultetu, Univerziteta u Beogradu.

Oblasti istraživanja i rada:

Rukovodi timom istraživača koji se bave fundamentalnim i primenjenim istraživanjima, koja se odnose na insulin i insulinu slične faktore rasta. Istraživačke aktivnosti su usmerene ka ispitivanju uticaja različitih fizioloških stanja i bolesti na IGF sistem kod ljudi i životinja (starenje, fizička aktivnost, metabolički poremećaji, tumor, oksidativni stres) i na analizu uticaja molekula mikrookoline na reaktivnost IGF receptora.

Članstvo u međunarodnim i nacionalnim organizacijama:

Član Međunarodnog udruženja za insulinu slične faktore rasta (od 2003. godine)
Član Srpskog hemijskog društva (od 1985. godine)
Član Biohemijskog društva Srbije (od 2011. godine)

Aktivnosti i druge odgovornosti:

Član Odbora za akreditaciju naučnoistraživačkih organizacija pri MPNTR Republike Srbije (2006-2010. godine)
Član Veća naučnih oblasti biotehničkih nauka pri Univerzitetu u Beogradu (2007-2010. godine)
Član redakcije časopisa Journal of the Serbian Chemical Society za oblast biohemije i biotehnologije (od 2006. godine)
Član Odbora za obezbeđenje i unapređenje kvaliteta Univerziteta u Beogradu (2008-2011. godine)
Član Matičnog naučnog odbora za hemiju pri MPNTR RS (2010-2016. godine)
Član Upravnog odbora INEP-a (2011-2017. godine.)
Član Upravnog odbora Srpskog hemijskog društva (od 2000. godine)
Član Saveta BU (2016-2018. godine)
Član Senata BU (od 2018. godine)

Član Matičnog naučnog odbora za biologiju (od 2017. godine)

Odabrani radovi (2013-2018):

Gligorijević N., Zámorová Križáková M., Penezić A., Katrlík J., Nedić O., Structural and functional changes of fibrinogen due to aging. Int J Biol Macromol 2018, 108:1028-1034.

Gligorijević N., Minić S., Križáková M., Katrlík J., Nedić O., Structural changes of fibrinogen as a consequence of cirrhosis. Thromb Res 2018, 166:43-49.

Nedić O, Drvenica I., Ausloos M., Dekanski A., Efficiency in managing peer-review of scientific manuscripts – editors’ perspective. J Serb Chem Soc 2018, 83:doi:10.2298/JSC180531066N.

Nedić O., Šunderić M., Miljuš G., Penezić A., Gligorijević N., Robajac D., Application of the lectin-affinity techniques: advances in the analysis and understanding of the insulin-like growth factor (IGF) system. In: Advances in Medicine and Biology Vol. 131. Nova Science Publishers, Hauppauge, NY. Editor: Leon V. Berhardt. 2018. p. 1-100. ISBN: 978-1-53613-840-5.

Robajac D., Zamorova M., Katrlik J., Miković Ž., Nedić O. Screening for the best detergent for the isolation of placental membrane proteins. Int J Biol Macromol, 2017, 102:431-437.

Penezić A., Miljuš G., Milutinović B., Nedić O., A microscale protocol for the isolation of transferrin directly from serum. Clin Chim Acta, 2017, 471:12-16.

Nedić O., Šunderić M., Miljuš G., Valdevit Z., Jakovljević V., Glibetić M., Vučić V. Preparatory training attenuates drastic response of the insulin-like growth factor binding protein 1 at the point of maximal oxygen consumption in handball players. J Sport Health Sci, 2017, 6:372-377.

Mrowinski M., Fronczak P., Fronczak A., Ausloos M., Nedić O., Artifical intelligence in peer review: how can evolutionary computation support journal editors. PLoS ONE, 2017, 12:Art. no. e0184711.

Robajac D., Gligorijević N., Dželetović Ž., Andrejić G., Nedić O., Separation of peroxidases from Miscanthus x giganteus, their partial characterisation and application for degradation of dyes. Plant Physiol Biochem, 2017, 120:179-185.

Gligorijević N., Penezić A., Nedić O., Influence of glyco-oxidation on complexes between fibrin(ogen) and insulin-like growth factor binding protein-1 in patients with diabetes mellitus type 2. Free Rad Res, 2017, 51:64-72.

Zamorova M., Holazova A., Miljuš G., Robajac D., Šunderić M., Malenković V., Djukanović B., Gemeiner P., Katrlik J., Nedić O., Analysis of changes in glycan composition of serum, cytosol and membrane glycoprotein biomarkers of colorectal cancer by lectin-based protein microarray. Anal Methods, 2017, 9:2660-2666.

Nedić O., Šunderić M., Gligorijević N., Malenković V., Miljuš G. Analysis of four circulating complexes of the insulin-like growth factor binding proteins in human blood during ageing. Biochemistry (Moscow), 2017, 10:1200-1206.

Ausloos M., Nedić O., Dekanski A. A day of the week effect in paper submission/acceptance/rejection to/in/by peer review journals. II. An ARCH econometric-like modelling. Physica A: Statis Mech Appl, 2017, 468:462-474.

Robajac D., Vanhooren V., Masnikosa R., Miković Ž., Mandić V., Libert C., Nedić O. Preeclampsia transforms membrane n-glycome in human placenta. Exp Mol Pathol, 2016, 100:26-30.

Robajac D., Nedić O., Miković Ž., Masnikosa R. Gestation-associated changes in the glycosylation of placental insulin and insluin-like growth factor receptors. Placenta, 2016, 39:70-76.

Šunderić M., Šediva A., Robajac D., Miljuš G., Gemeiner P., Nedić O., Katrlik J. Lectin-based protein microarray analysis of differences in serum alpha-2-macroglobulin glycosylation between patients with colorectal cancer and noncancer persons. Biotechnol Appl Biochem, 2016, 63:457-464.

Nedić O., Miljuš G., Malenković V. Regulation of insulin and insulin-like activity in malnourished patients with carcinoma ventriculi subjected to total gastrectomy and personalized nutritional support. J Med Biochem, 2016, 35:17-25.

Gligorijević N., Nedić O. Interaction between fibrinogen and insulin-like growth factor-binding protein-1 in human plasma under physiologic conditions. Biochemistry (Moscow), 2016, 81:135-140.

Ausloos M., Nedić O., Fronczak A., Fronczak P., Quantifying the quality of peer reviewers through zipf’s law. Scientometrics, 2016, 106:347-368.

Nedić O., Dekanski A. Priority criteria in peer review of scientific articles. Scientometrics, 2016, 107:15-26.

Mrowinski M., Fronczak A., Fronczak P., Nedić O., Ausloos M. Review time in peer review: quantitative analysis and modelling of editorial workfows. Scientometrics, 2016, 107:271-286.

Ausloos M., Nedić O., Dekanski A. A day of the week effect in paper submission/acceptance/rejection to/in/by peer review journals. Physica A: Statist Mech Appl, 2016, 456:197-203.

Dekanski A., Drvenica I., Nedić O. Peer-review process in journals dealing with chemistry and related subjects published in Serbia. Chem Ind Chem Eng Quart, 2016, doi. 10.2298/CICEQ160328033D.

Gligorijević N., Penezić A., Nedić O. Influence of glyco-oxidation on complexes between fibrin(ogen) and insulin-like growth factor binding protein-1 in patients with diabetes mellitus type 2. Free Rad Res, 2016, 5:1-28.

Šunderić M., Malenković V., Nedić O. Complexes between insulin-like growth factor binding proteins and alpha-2-macroglobulin in patients with tumor. Exp Mol Pathol, 2015, 98:173-177.

Miljuš G., Malenković V., Djukanović B., Kolundžić N., Nedić O. IGFBP-3/transferrin/transferrin receptor 1 complexes as principal mediators of IGFBP-3 delivery to colon cells in non-cancer and cancer tissue. Exp Mol Pathol, 2015, 98:431-438.

Robajac D., Masnikosa R., Miković Ž., Mandić V., Nedić O. Oxidation of placental insulin and insulin-llike growth factor receptors in mothers with diabetes mellitus or preeclampsia complicated with intrauterine growth restriction. Free Rad Res, 2015, 49:984-989.

Nedić O., Dekanski A. A survey on the publishing policies of the Journal of the Serbian Chemical Society-On the occasion of the 80th volume. J Serb Chem Soc, 2015, 80:959-969.

Nedić O., Rogowska-Wrzesinska A., Rattan S.I.S. Standardization and quality control in quantifying non-enzymatic oxidative protein modifications in relation to ageing and disease: Why is it important and why is it hard. Redox Biol, 2015, 4:91-100.

Robajac D., Masnikosa R., Vanhooren V., Libert C., Miković Ž., Nedić O. The N-glycan profile of placental membrane glycoproteins alters during gestation and ageing. Mech Ageing Develop, 2014, 138:1-9.

Šunderić M., Djukanović B., Malenković V., Nedić O. Molecular forms of insulin-like growth factor-binding protein-2 in patients with colorectal cancer. Exp Mol Pathol, 2014, 96:48-53.

Šunderić M., Mihailović N., Nedić O. Protein molecular forms of the insulin-like growth factor binding protein 2 change with ageing. Exp Gerontol, 2014, 58:154-158.

Rogowska-Wrzesinska A., Wojdyla K., Nedić O., Baron C.P., Griffiths H. Analysis of protein carbonylation-pitfalls and promise in commonly used methods. Free Rad Res, 2014, 48:1145-1162.

Miljuš G., Malenković V., Nedić O. The importance of metal ion for the formation and isolation of insulin-like growth factor-binding protein 3/transferrin (IGFBP-3/TF) complexes, and the analysis of their physiological involvement. Metallomics, 2013, 5:251-258.

Nedić O., Robajac D., Šunderić M., Miljuš G., Djukanović B., Malenković V. Detection and identification of the oxidized insulin-like growth factor binding proteins and receptors in patients with colorectal carcinoma. Free Rad Biol Med, 2013, 65:1195-1200.

Lagundžin D., Vučić V., Glibetić M., Nedić O. Alteration of IGFBP-1 in soccer players due to intensive training. Int J Sport Nutr Exerc Metab, 2013, 23:449-457.

Nedić O., Rattan S.I.S., Grune T., Trougakos I.P. Molecular effects of advanced glycation end products (AGEs) on cell signalling pathways, ageing and pathophysiology. Free Rad Res, 2013, 47 (Suppl.1):28-38.

Nedić O., Malenković V., Djukanović B., Baričević I. Ligand-binding activity and immunoreactivity of the insulin-like growth factor binding proteins in patients with colorectal carcinoma and post-operative sepsis. J Med Biochem, 2013, 32:250-255.

Šunderić M., Miljuš G., Nedić O. Interaction of insulin-like growth factor-binding protein 2 with alpha 2-macroglobulin in the circulation. Prot J, 2013, 32:138-142.

Bibliografija:

https://orcid.org/0000-0003-2042-0056
ORCID ID:  0000-0003-2042-0056