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Olgica Nedić

Organizaciona jedinica: Odeljenje za metabolizam

Profil/Akademsko zvanje: Diplomirani hemičar, doktor biohemijskih nauka

Naučno zvanje: Naučni savetnik

Rukovodeće funkcije: Direktor Instituta i Načelnik Odeljenja za metabolizam

Rukovodilac istraživačke teme: „Proteini i nukleinske kiseline u metaboličkim poremećajima i mehanizmi njihove regulacije“.

Osnovne studije: Završila Prirodno-matematički fakultet Univerziteta u Beogradu 1985. godine, magistrirala 1988. i doktorirala 1994. godine na Hemijskom fakultetu, Univerziteta u Beogradu.

Oblasti istraživanja i rada:

Rukovodi timom istraživača koji se bave fundamentalnim i primenjenim istraživanjima koja se odnose na insulin, insulinu slične faktore rasta i druge proteine koji učestvuju u metaboličkim procesima. Istraživačke aktivnosti su usmerene ka ispitivanju uticaja različitih fizioloških stanja i bolesti na metabolizam kod ljudi i životinja (starenje, fizička aktivnost, trudnoća, dijabetes, tumor, bolesti praćene oksidativnim stresom) i na analizu potencijalnog efekta malih molekula iz mikrookoline. Osim ispitivanja proteina, istraživanja se odnose na anlizu nekodirajućih nukleinskih kiselina i njihovu povezanost sa metaboličkim poremećajima.

Članstvo u međunarodnim i nacionalnim organizacijama:

Član Međunarodnog udruženja za insulinu slične faktore rasta (od 2003. godine)
Član Srpskog hemijskog društva (od 1985. godine)
Član Biohemijskog društva Srbije (od 2011. godine)

Aktivnosti i druge odgovornosti:

Član Odbora za akreditaciju naučnoistraživačkih organizacija pri MPNTR Republike Srbije (2006-2010. godine)
Član Veća naučnih oblasti biotehničkih nauka pri Univerzitetu u Beogradu (2007-2010. godine)
Član redakcije časopisa Journal of the Serbian Chemical Society za oblast biohemije i biotehnologije (od 2006. godine)
Član Odbora za obezbeđenje i unapređenje kvaliteta Univerziteta u Beogradu (2008-2011. godine)
Član Matičnog naučnog odbora za hemiju pri MPNTR RS (2010-2016. godine)
Član Upravnog odbora INEP-a (2011-2017. godine.)
Član Upravnog odbora Srpskog hemijskog društva (od 2000. godine)
Član Saveta BU (2016-2018. godine)
Član Senata BU (2018. godine)

Član Matičnog naučnog odbora za biologiju (od 2017. godine)

Odabrani radovi (2013-2019):

Gligorijević N., Minić S., Robajac D., Nikolić M., Ćirković Veličković T., Nedić, O., Characterisation and the effects of bilirubin binding to human fibrinogen. Int J Biol Macromol 2019, 128:74-79.

Penezić A., Križakova M., Miljuš G., Katrlik J., Nedić O., Diagnostic potential of transferrin glycoforms – a lectin-based protein microarray approach. Proteom Clin Appl 2019, 13:Art. No. 1800185.

Šunderić M., Robajac D., Gligorijević N., Miljuš G., Nedić O., Smilkov K., Gjorgieva Ackova D., Rudić-Grujić V., Penezić A., Is there something fishy about fish oil? Curr Pharmaceut Design 2019, 25:1747-1759.

Šunderić M., Križakova M., Malenković V., Ćujić D., Katrlik J., Nedić O., Changes due to ageing in the glycan structure of alpha-2-macroglobulin and its reactivity with ligands. Prot J 2019, 38:23-29.

Gligorijević N., Šunderić M., Vilotić A., Baralić M., Nedić O., Quantitation of the active alpha-2-macroglobulin by trypsin protease zymography. J Serb Chem Soc 2019, 84:943-950.

Gligorijević N., Robajac D., Nedić O., An enhanced platelet sensitivity to IGF-I in patients with diabetes mellitus. Biochemistry 2019, 84:1213-1219.

Robajac D., Masnikosa R., Nemčovič M., Križáková M., Belická Kluková L., Baráth P., Katrlik J., Nedic O., Glycoanalysis of the placental membrane glycoproteins throughout placental development. Mech Age Develop 2019, 83:Art. no. 111151.

Ausloos M., Nedic O., Dekanski A., Correlations between submission and acceptance of papers in peer review journals. Scientometrics 2019, 119:279-302.

Ausloos M., Nedic O., Dekanski A., Seasonal entropy, diversity and inequality measures of submitted and accepted papers distributions in peer review journals. Entropy 2019, 21:Art. No. 564.

Lagundžin D., Hu W., Law H. C. H., Krieger K., L., Qiao F., Clement E. J., Drincic A. T., Nedić O., Naldrett M. J., Alvarez S., Woods T. N., Delineating the role of FANCA in glucose-stimulated insulin secretion in B cells through its protein interactome. PLoS ONE 2019, 12:Art. no. 0220568.

Drvenica I., Bravo G., Vejmelka L., Dekanski A., Nedić O., Peer review of reviewers: the author’s perspective. Publications 2019, 7:Art. No. 1, doi:10.3390/publications7010001.

Drvenica I. T., Dekanski A. B., Budjevac N., Umeljić I., Nedić O., Is there a need for systematic education on peer-reviewing in Serbia? Hem ind 2019, 73:275-279.

Gligorijević N., Zámorová Križáková M., Penezić A., Katrlík J., Nedić O., Structural and functional changes of fibrinogen due to aging. Int J Biol Macromol 2018, 108:1028-1034.

Gligorijević N., Minić S., Križáková M., Katrlík J., Nedić O., Structural changes of fibrinogen as a consequence of cirrhosis. Thromb Res 2018, 166:43-49.

Nedić O, Drvenica I., Ausloos M., Dekanski A., Efficiency in managing peer-review of scientific manuscripts – editors’ perspective. J Serb Chem Soc 2018, 83:1391-1405.

Nedić O., Šunderić M., Miljuš G., Penezić A., Gligorijević N., Robajac D., Application of the lectin-affinity techniques: advances in the analysis and understanding of the insulin-like growth factor (IGF) system. In: Advances in Medicine and Biology Vol. 131. Nova Science Publishers, Hauppauge, NY. Editor: Leon V. Berhardt. 2018. p. 1-100. ISBN: 978-1-53613-840-5.

Robajac D., Zamorova M., Katrlik J., Miković Ž., Nedić O. Screening for the best detergent for the isolation of placental membrane proteins. Int J Biol Macromol, 2017, 102:431-437.

Penezić A., Miljuš G., Milutinović B., Nedić O., A microscale protocol for the isolation of transferrin directly from serum. Clin Chim Acta, 2017, 471:12-16.

Nedić O., Šunderić M., Miljuš G., Valdevit Z., Jakovljević V., Glibetić M., Vučić V. Preparatory training attenuates drastic response of the insulin-like growth factor binding protein 1 at the point of maximal oxygen consumption in handball players. J Sport Health Sci, 2017, 6:372-377.

Mrowinski M., Fronczak P., Fronczak A., Ausloos M., Nedić O., Artifical intelligence in peer review: how can evolutionary computation support journal editors. PLoS ONE, 2017, 12:Art. no. e0184711.

Robajac D., Gligorijević N., Dželetović Ž., Andrejić G., Nedić O., Separation of peroxidases from Miscanthus x giganteus, their partial characterisation and application for degradation of dyes. Plant Physiol Biochem, 2017, 120:179-185.

Gligorijević N., Penezić A., Nedić O., Influence of glyco-oxidation on complexes between fibrin(ogen) and insulin-like growth factor binding protein-1 in patients with diabetes mellitus type 2. Free Rad Res, 2017, 51:64-72.

Zamorova M., Holazova A., Miljuš G., Robajac D., Šunderić M., Malenković V., Djukanović B., Gemeiner P., Katrlik J., Nedić O., Analysis of changes in glycan composition of serum, cytosol and membrane glycoprotein biomarkers of colorectal cancer by lectin-based protein microarray. Anal Methods, 2017, 9:2660-2666.

Nedić O., Šunderić M., Gligorijević N., Malenković V., Miljuš G. Analysis of four circulating complexes of the insulin-like growth factor binding proteins in human blood during ageing. Biochemistry (Moscow), 2017, 10:1200-1206.

Ausloos M., Nedić O., Dekanski A. A day of the week effect in paper submission/acceptance/rejection to/in/by peer review journals. II. An ARCH econometric-like modelling. Physica A: Statis Mech Appl, 2017, 468:462-474.

Robajac D., Vanhooren V., Masnikosa R., Miković Ž., Mandić V., Libert C., Nedić O. Preeclampsia transforms membrane n-glycome in human placenta. Exp Mol Pathol, 2016, 100:26-30.

Robajac D., Nedić O., Miković Ž., Masnikosa R. Gestation-associated changes in the glycosylation of placental insulin and insluin-like growth factor receptors. Placenta, 2016, 39:70-76.

Šunderić M., Šediva A., Robajac D., Miljuš G., Gemeiner P., Nedić O., Katrlik J. Lectin-based protein microarray analysis of differences in serum alpha-2-macroglobulin glycosylation between patients with colorectal cancer and noncancer persons. Biotechnol Appl Biochem, 2016, 63:457-464.

Nedić O., Miljuš G., Malenković V. Regulation of insulin and insulin-like activity in malnourished patients with carcinoma ventriculi subjected to total gastrectomy and personalized nutritional support. J Med Biochem, 2016, 35:17-25.

Gligorijević N., Nedić O. Interaction between fibrinogen and insulin-like growth factor-binding protein-1 in human plasma under physiologic conditions. Biochemistry (Moscow), 2016, 81:135-140.

Ausloos M., Nedić O., Fronczak A., Fronczak P., Quantifying the quality of peer reviewers through zipf’s law. Scientometrics, 2016, 106:347-368.

Nedić O., Dekanski A. Priority criteria in peer review of scientific articles. Scientometrics, 2016, 107:15-26.

Mrowinski M., Fronczak A., Fronczak P., Nedić O., Ausloos M. Review time in peer review: quantitative analysis and modelling of editorial workfows. Scientometrics, 2016, 107:271-286.

Ausloos M., Nedić O., Dekanski A. A day of the week effect in paper submission/acceptance/rejection to/in/by peer review journals. Physica A: Statist Mech Appl, 2016, 456:197-203.

Dekanski A., Drvenica I., Nedić O. Peer-review process in journals dealing with chemistry and related subjects published in Serbia. Chem Ind Chem Eng Quart, 2016, doi. 10.2298/CICEQ160328033D.

Gligorijević N., Penezić A., Nedić O. Influence of glyco-oxidation on complexes between fibrin(ogen) and insulin-like growth factor binding protein-1 in patients with diabetes mellitus type 2. Free Rad Res, 2016, 5:1-28.

Šunderić M., Malenković V., Nedić O. Complexes between insulin-like growth factor binding proteins and alpha-2-macroglobulin in patients with tumor. Exp Mol Pathol, 2015, 98:173-177.

Miljuš G., Malenković V., Djukanović B., Kolundžić N., Nedić O. IGFBP-3/transferrin/transferrin receptor 1 complexes as principal mediators of IGFBP-3 delivery to colon cells in non-cancer and cancer tissue. Exp Mol Pathol, 2015, 98:431-438.

Robajac D., Masnikosa R., Miković Ž., Mandić V., Nedić O. Oxidation of placental insulin and insulin-llike growth factor receptors in mothers with diabetes mellitus or preeclampsia complicated with intrauterine growth restriction. Free Rad Res, 2015, 49:984-989.

Nedić O., Dekanski A. A survey on the publishing policies of the Journal of the Serbian Chemical Society-On the occasion of the 80th volume. J Serb Chem Soc, 2015, 80:959-969.

Nedić O., Rogowska-Wrzesinska A., Rattan S.I.S. Standardization and quality control in quantifying non-enzymatic oxidative protein modifications in relation to ageing and disease: Why is it important and why is it hard. Redox Biol, 2015, 4:91-100.

Robajac D., Masnikosa R., Vanhooren V., Libert C., Miković Ž., Nedić O. The N-glycan profile of placental membrane glycoproteins alters during gestation and ageing. Mech Ageing Develop, 2014, 138:1-9.

Šunderić M., Djukanović B., Malenković V., Nedić O. Molecular forms of insulin-like growth factor-binding protein-2 in patients with colorectal cancer. Exp Mol Pathol, 2014, 96:48-53.

Šunderić M., Mihailović N., Nedić O. Protein molecular forms of the insulin-like growth factor binding protein 2 change with ageing. Exp Gerontol, 2014, 58:154-158.

Rogowska-Wrzesinska A., Wojdyla K., Nedić O., Baron C.P., Griffiths H. Analysis of protein carbonylation-pitfalls and promise in commonly used methods. Free Rad Res, 2014, 48:1145-1162.

Miljuš G., Malenković V., Nedić O. The importance of metal ion for the formation and isolation of insulin-like growth factor-binding protein 3/transferrin (IGFBP-3/TF) complexes, and the analysis of their physiological involvement. Metallomics, 2013, 5:251-258.

Nedić O., Robajac D., Šunderić M., Miljuš G., Djukanović B., Malenković V. Detection and identification of the oxidized insulin-like growth factor binding proteins and receptors in patients with colorectal carcinoma. Free Rad Biol Med, 2013, 65:1195-1200.

Lagundžin D., Vučić V., Glibetić M., Nedić O. Alteration of IGFBP-1 in soccer players due to intensive training. Int J Sport Nutr Exerc Metab, 2013, 23:449-457.

Nedić O., Rattan S.I.S., Grune T., Trougakos I.P. Molecular effects of advanced glycation end products (AGEs) on cell signalling pathways, ageing and pathophysiology. Free Rad Res, 2013, 47 (Suppl.1):28-38.

Nedić O., Malenković V., Djukanović B., Baričević I. Ligand-binding activity and immunoreactivity of the insulin-like growth factor binding proteins in patients with colorectal carcinoma and post-operative sepsis. J Med Biochem, 2013, 32:250-255.

Šunderić M., Miljuš G., Nedić O. Interaction of insulin-like growth factor-binding protein 2 with alpha 2-macroglobulin in the circulation. Prot J, 2013, 32:138-142.

Bibliografija:

https://orcid.org/0000-0003-2042-0056
ORCID ID:  0000-0003-2042-0056